NF-κB Luciferase Reporter A549 Cell Line is an A549 cell line expressing the NF-κB luciferase reporter. The firefly luciferase gene is controlled by 4 copies of NF-κB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase reporter. This cell line has been validated for NF-κB stimulation by TNFα and IL-1?.

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