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●Purchase●DescriptionI-BET151(GSK1210151A)isaBETbromodomaininhibitor
產(chǎn)品型號(hào):27629-1
廠商性質(zhì):生產(chǎn)廠家
更新時(shí)間:2023-11-11
訪 問 量:112
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I-BET151(GSK1210151A) is a BET bromodomain inhibitor. I-BET151 displays potent binding affinity to BRD2, BRD3 and BRD4 with Kd of 0.02-0.1 µM. I-BET151 (0.5 or 5 µM) inhibits the binding of BETs (BRD2, BRD3, BRD4, and BRD9) but not the binding of 23 other bromodomain proteins. I-BET151 also blocks recruitment of BET to chromatin.
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