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XAV939

●Purchase●DescriptionXAV939isasmallmoleculeandselectiveWntpathwaytranscriptionfactor-catenin-mediatedtranscriptioninhibitorandaxinstabilizingagent

  • 產品型號:27100
  • 廠商性質:生產廠家
  • 更新時間:2023-11-10
  • 訪  問  量:144
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Description

XAV 939 is a small molecule and selective Wnt pathway transcription factor - catenin-mediated transcription inhibitor and axin stabilizing agent. It stimulates beta-catenin degradation by stabilizing axin, the concentration-limiting component of the destruction complex and stabilizes axin by inhibiting the poly-ADP-ribosylating enzymes tankyrase 1 (TNKS1) and tankyrase 2 (TNKS2).

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