18禁免费网站,亚洲风情海量免费久久视频,精品人妻一区二区三区浪,水多多www视频在线观看高清

熱門搜索: 50072ATAT1, GST-tag Recombinant 40520ATF2, GST-Tag Recombinant 31114GCN5 (727-837), His-tag Recombinant 50074GCN5 (KAT2A), FLAG-tag Recombinant 50071p300 (KAT3B), His-GST-tag Recombinant 11004ACHE, His-Tag Recombinant 50272BCL-2, His-Tag Recombinant 100077BCL2A1, His-Tag Recombinant 100080BCL2L10, His-Tag Recombinant 100091BCL2L2, His-Tag Recombinant 80113Caspase6, His-tag Recombinant 70000Caspase7, His-tag Recombinant 80114Caspase8, His-tag Recombinant 100543GPX4, FLAG-Tag Recombinant 100054MALT1, FLAG-Tag (Mouse) Recombinant 100637MCL-1 His-Tag (Mouse) Recombinant

產(chǎn)品展示/ Product display

您的位置:首頁(yè)  /  產(chǎn)品展示  /    /  細(xì)胞庫(kù) / 細(xì)胞培養(yǎng)  /  IRF Reporter (Luc) - THP-1 Cell line (cGAS-Sting Signaling Pathway)

IRF Reporter (Luc) - THP-1 Cell line (cGAS-Sting Signaling Pathway)

  • 產(chǎn)品型號(hào):
  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時(shí)間:2023-10-12
  • 訪  問  量:255
立即咨詢

聯(lián)系電話:

詳細(xì)介紹
  • 數(shù)量:

    1

  • 供應(yīng)商:

    BPS Bioscience

  • 細(xì)胞類型:

    穩(wěn)轉(zhuǎn)細(xì)胞系

  • 品系:

    THP-1

  • 組織來源:

    /

  • 相關(guān)疾?。?/span>

    多種

  • 物種來源:

    human

  • 免疫類型:

    多種

  • 器官來源:

  • 運(yùn)輸方式:

    干冰

  • 年限:

    10

  • 生長(zhǎng)狀態(tài):

    良好

  • CAS號(hào):

  • 英文名:

    IRF Reporter (Luc) - THP-1 Cell line (cGAS-Sting Signaling Pathway)

  • 注冊(cè)證號(hào):

    /

  • 規(guī)格:

    2管

The Interferon Regulatory Factor (IRF) reporter (Luc)-THP-1 cell line is designed to study the activation and signaling of Cytosolic DNA Sensors (CDS) in human monocytic cell line THP-1. It contains a firefly luciferase gene driven by multimerized ISRE (Interferon Stimulated Response Element) located upstream of the minimal TATA promoter. The cGAS-STING pathway acts to detect cytosolic DNA and induce an immune response. Briefly, upon binding DNA, the protein cGAS (cyclic GMP-AMP Synthase) triggers reaction of GTP and ATP to form cGAMP. cGAMP binds to STING (Stimulator of Interferon Genes) which triggers phosphorylation of IRF3 via TBK1. IRF3 can then bind to interferon-stimulated responsive elements (ISRE) in the nucleus and leads to IFN-α/β production. The IRF reporter (Luc)-THP-1 cell line is highly responsive to STING and CDS ligands.

留言詢價(jià)

留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細(xì)地址:

  • 補(bǔ)充說明:

  • 驗(yàn)證碼:

    請(qǐng)輸入計(jì)算結(jié)果(填寫阿拉伯?dāng)?shù)字),如:三加四=7
關(guān)注公眾號(hào)

郵箱:infocn@bpsbioscience.com

傳真:

地址:上海靜安區(qū)

Copyright © 2025 BPS Bioscience Inc.版權(quán)所有   備案號(hào):   技術(shù)支持:化工儀器網(wǎng)

TEL:

掃碼加微信